Comparison of azlocillin, ceftizoxime, cefoxitin, and amikacin alone and in combination against Pseudomonas aeruginosa in a neutropenic-site rabbit model
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منابع مشابه
Activities of tobramycin and azlocillin alone and in combination against experimental osteomyelitis caused by Pseudomonas aeruginosa.
Azlocillin and tobramycin were used alone and in combination in the treatment of chronic osteomyelitis due to Pseudomonas aeruginosa in rabbits. This combination showed in vitro synergy measured by both the checkerboard technique and time-kill curves. A marked inoculum effect was demonstrated in vitro with azlocillin and the infecting strain of P. aeruginosa. The minimal inhibitory concentratio...
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Ceftriaxone, a new third-generation cephalosporin with a very long serum half-life, has been shown to have a wide antimicrobial spectrum. Its activity against Pseudomonas aeruginosa, however, is rather limited (1, 5, 6, 8). The in vitro activity of ceftriaxone against 50 P. aeruginosa strains by the broth dilution method and the effects of combining ceftriaxone with gentamicin, tobramycin, or a...
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In vitro activity of ceftriaxone alone and in combination with gentamicin, tobramycin, and amikacin against Pseudomonas aeruginosa.
The in vitro activity of ceftriaxone alone and in combination with gentamicin, tobramycin, and amikacin against 50 Pseudomonas aeruginosa strains was studied by the broth dilution method and the time-kill curve method. The majority of the P. aeruginosa strains tested were resistant to ceftriaxone. Combining ceftriaxone with the aminoglycosides resulted in synergism, antagonism, or indifference.
متن کاملIn vitro activities of ureidopenicillins alone and in combination with amikacin and three cephalosporin antibiotics.
The MIC and MBC activity of mezlocillin alone and in combination with two concentrations of ceftizoxime, moxalactam, and amikacin and a single concentration of cefoxitin was studied in a broth microdilution partial checkerboard against 472 strains of aerobic gram-negative and gram-positive bacteria. Azlocillin was tested alone and in the same combinations against Pseudomonas aeruginosa. Of the ...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1984
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.25.5.545